7 Mar 2006 Building A, First Floor, De Pintelaan 185, 9000 Ghent, Belgium; Hepatitis C virus (HCV) is a major cause of chronic liver disease, . 4, which is published as supporting information on the PNAS web site). been no reliable methods to culture clinical isolates of HCV to date. .. Abstract/FREE Full Text.
14 Mar 2012 Coalescent inference has been used to date the origin of HCV in .. Only in one example—subtype 3a in Belgium—was the SIS model most probable (PP = 0.88). . However, there is evidence to suggest that the rate may be closer to 1.0 × 10−3 per site per year [26,72]. . OpenUrlAbstract/FREE Full Text.